Detection of occult hemorrhage (i.e., internal bleeding) in patients in intensive care units (ICUs) can pose significant challenges for critical care workers. Because blood loss may not always be clinically apparent, clinicians rely on monitoring vital signs for specific trends indicative of a hemorrhage event. The inherent difficulties of diagnosing such an event can lead to late intervention by clinicians which has catastrophic consequences. Therefore, a methodology for early detection of hemorrhage has wide utility. We develop a Bayesian regime switching model (RSM) that analyzes trends in patients' vitals and labs to provide a probabilistic assessment of the underlying physiological state that a patient is in at any given time. This article is motivated by a comprehensive dataset we curated from Mayo Clinic of 33,924 real ICU patient encounters. Longitudinal response measurements are modeled as a vector autoregressive process conditional on all latent states up to the current time point, and the latent states follow a Markov process. We present a novel Bayesian sampling routine to learn the posterior probability distribution of the latent physiological states, as well as develop an approach to account for pre-ICU-admission physiological changes. A simulation and real case study illustrate the effectiveness of our approach.

While the setting of state-only demonstrations is not common, there are certain exceptions.

Modeling the human as Boltzmann-rational w.r.t. a belief over trajectories, we prove conditions under which RLHF is

In many cases, the correlation exists between not only events' emitted

In this study, we develop an approach to multivariate time series anomaly detection focused on the transformation of multivariate time series to univariate time series. Several transformation techniques involving Fuzzy C-Means (FCM) clustering and fuzzy integral are studied. In the sequel, a Hidden Markov Model (HMM), one of the commonly encountered statistical methods, is engaged here to detect anomalies in multivariate time series. We construct HMM-based anomaly detectors and in this context compare several transformation methods. A suite of experimental studies along with some comparative analysis is reported.

Modeling the human as Boltzmann-rational w.r.t. a belief over trajectories, we prove conditions under which RLHF is